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Dr. Marie Renault, Dr. Shane Pawsey, Dr. Martine P. Bos, Eline J. Koers, Dr. Deepak Nand, Ria Tommassen-van Boxtel, Dr. Melanie Rosay, Prof. Jan Tommassen, Dr. Werner E. Maas and Prof. Marc Baldus Solid-State NMR Spectroscopy on Cellular Preparations Enhanced by Dynamic Nuclear Polarization Angewandte Chemie International Edition 51

Version of Record online: 1 FEB 2012 | DOI: 10.1002/anie.201105984

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A peek inside: Dynamic nuclear polarization (DNP) enhances the spectroscopic sensitivity of solid-state NMR measurements of uniformly (13C,15N)-labeled preparations of Escherichia coli cells by more than an order of magnitude (see picture; MW=microwaves, ε=enhancement factor). The major molecular components in the cells can be characterized in this way.

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