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Dr. Gonçalo J. L. Bernardes, Dr. Giulio Casi, Dr. Sabrina Trüssel, Isabelle Hartmann, Dr. Kathrin Schwager, Dr. Jörg Scheuermann and Prof. Dario Neri A Traceless Vascular-Targeting Antibody–Drug Conjugate for Cancer Therapy Angewandte Chemie International Edition 51

Version of Record online: 15 DEC 2011 | DOI: 10.1002/anie.201106527

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Right on target: A chemically defined vascular-targeting antibody–drug conjugate (ADC) that offers comprehensive tumor coverage has been developed. When injected intravenously, this ADC potently inhibited tumor growth in a syngeneic immunocompetent model of murine cancer which cannot be cured by conventional cytotoxic agents.

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