E-mail a Wiley Online Library Link

Thomas Schmidt and Prof. Dr. Andreas Kirschning Total Synthesis of Carolacton, a Highly Potent Biofilm Inhibitor Angewandte Chemie International Edition 51

Version of Record online: 9 DEC 2011 | DOI: 10.1002/anie.201106762

Thumbnail image of graphical abstract

Metals are the key players in the synthesis of caralacton, a strong inhibitor of bacterial biofilms. The total synthesis is based on several metal-mediated key transformations such as the Ley and the Duthaler–Hafner aldol reactions, the Marshall reaction and Breit's substitution, as well as the Nozaki–Hiyama–Kishi and Negishi–Fu C[BOND]C coupling reactions.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field