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Dr. Carin C. C. Johansson Seechurn, Dr. Matthew O. Kitching, Dr. Thomas J. Colacot and Prof. Victor Snieckus Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize Angewandte Chemie International Edition 51

Version of Record online: 9 MAY 2012 | DOI: 10.1002/anie.201107017

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The 2010 Nobel Prize in Chemistry was awarded to Richard Heck, Ei-ichi Negishi, and Akira Suzuki for their contributions to the development of Pd-catalyzed C[BOND]C bond forming reactions. This Review traces the historical origins of the reactions these laureates discovered, and follows the three waves of research (see scheme) that led to the systematic evolution of “cross-coupling” and the resultant proliferation of discovery within the field of metal-catalyzed organic transformations to the present time.

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