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Dr. Cole A. DeForest and Prof. Kristi S. Anseth Back Cover: Photoreversible Patterning of Biomolecules within Click-Based Hydrogels (Angew. Chem. Int. Ed. 8/2012) Angewandte Chemie International Edition 51

Version of Record online: 8 DEC 2011 | DOI: 10.1002/anie.201108165

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Reversible biomolecular patterning in hydrogels can direct cell function in a user-defined manner. In their Communication on page 1816 ff., K. S. Anseth and C. A DeForest report 4D spatiotemporal control over the presentation of bioligands by using a thiol–ene photoconjugation reaction, which is initiated by visible light, combined with the photocleavage of an o-nitrobenzyl ether, which is controlled by UV light. This method allows cell functions to be probed dynamically.

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