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Dr. Eiji Nakata, Dr. Fong Fong Liew, Chisana Uwatoko, Dr. Shigeki Kiyonaka, Prof. Dr. Yasuo Mori, Yousuke Katsuda, Dr. Masayuki Endo, Prof. Dr. Hiroshi Sugiyama and Prof. Dr. Takashi Morii Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures Angewandte Chemie International Edition 51

Article first published online: 27 JAN 2012 | DOI: 10.1002/anie.201108199

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Point the finger: Zinc-finger proteins are convenient and site-selective adaptors for targeting specific locations within DNA-origami structures. Orthogonal targeting of the specific locations in the structures was demonstrated by using two adaptors, and the application of Escherichia coli lysate that contained the adaptor-fused proteins successfully afforded the expected protein–DNA assembly.

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