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Prof. Dr. Paolo Melchiorre Cinchona-based Primary Amine Catalysis in the Asymmetric Functionalization of Carbonyl Compounds Angewandte Chemie International Edition 51

Article first published online: 15 AUG 2012 | DOI: 10.1002/anie.201109036

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Primary choice: In only five years, cinchona-based primary amine catalysis has almost equaled the high level of efficiency and reliability of aminocatalysis by proline-derived catalysts, offering the unique possibility of effecting reactions between sterically demanding carbonyl compounds (see picture).

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