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Shengtao Ding and Dr. Ning Jiao N,N-Dimethylformamide: A Multipurpose Building Block Angewandte Chemie International Edition 51

Article first published online: 28 AUG 2012 | DOI: 10.1002/anie.201200859

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All-purpose reagent: In addition to being an effective polar solvent for chemical reactions, N,N-dimethylformamide (DMF) can serve as the source for a variety of units, such as CHO, CHNMe2, C(O)NMe2, NMe2, and CN among others (see scheme). Recent developments in the employment of DMF as a reactant are reviewed.

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