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Lai-Sheung Choi and Hagan Bayley S-Nitrosothiol Chemistry at the Single-Molecule Level Angewandte Chemie International Edition 51

Article first published online: 4 JUL 2012 | DOI: 10.1002/anie.201202365

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SNO patrol: S-Nitrosothiols (RSNO) are important molecules involved in cell signaling, which control physiological processes such as vasodilation and bronchodilation. By using the protein pore α-hemolysin as a nanoreactor, the biological chemistry of RSNO has been investigated at the single-molecule level (see scheme).

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