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Dr. Guillaume Bort, Dr. Thibault Gallavardin, Dr. David Ogden and Dr. Peter I. Dalko From One-Photon to Two-Photon Probes: “Caged” Compounds, Actuators, and Photoswitches Angewandte Chemie International Edition 52

Version of Record online: 18 FEB 2013 | DOI: 10.1002/anie.201204203

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A leading light: Molecular systems that can be remotely controlled by light are gaining increasing importance in cell biology and neurosciences because of the spatial and temporal precision that is achievable with laser microscopy. Two-photon excitation has significant advantages over one-photon approaches deep in biological tissues, but the design of “smart” probes compatible with cell physiology is challenging.

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