E-mail a Wiley Online Library Link

Qiankun Li, Prof. Dr. Chunling Fu and Prof. Dr. Shengming Ma Catalytic Asymmetric Allenylation of Malonates with the Generation of Central Chirality Angewandte Chemie International Edition 51

Article first published online: 10 OCT 2012 | DOI: 10.1002/anie.201204346

Thumbnail image of graphical abstract

Water plays an important role in a palladium-catalyzed allenylation of diethyl malonate with 2,3-allenyl acetates to yield centrally chiral allenyl malonates bearing synthetically useful functional groups (see scheme). The products were formed with 92–96 % ee in the presence of a bulky, electron-rich biphenyl ligand at room temperature.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.