E-mail

E-mail a Wiley Online Library Link

James R. Frost, Dr. Colin M. Pearson, Dr. Thomas N. Snaddon, Dr. Richard A. Booth and Prof. Steven V. Ley Convergent Total Syntheses of Callipeltosides A, B, and C Angewandte Chemie International Edition 51

Version of Record online: 22 AUG 2012 | DOI: 10.1002/anie.201204868

Thumbnail image of graphical abstract

Going for the hat-trick: The synthesis of the entire callipeltoside family of natural products is described. Key to this synthesis was the coupling of the di-ene-yne and pyran fragments by a diastereoselective alkenylzinc addition allowing rapid access to the common aglycon. Attachment of each relevant L-configured sugar resulted in the first total synthesis of callipeltoside B (see scheme), and the syntheses of callipeltosides A and C.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH