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Abraham K. Badu-Tawiah, Anyin Li, Fred P. M. Jjunju and Prof. R. Graham Cooks Peptide Cross-Linking at Ambient Surfaces by Reactions of Nanosprayed Molecular Cations Angewandte Chemie International Edition 51

Version of Record online: 17 AUG 2012 | DOI: 10.1002/anie.201205044

Thumbnail image of graphical abstract

Chemical synthesis with ambient ions: Peptide cross-linking is achieved nearly instantaneously and quantitatively by delivering solvated peptide cations in microdroplets to a cross-linker present on a glass surface (see picture) or vice versa. The reaction can be carried out in an open laboratory environment.

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