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Dr. Reto Horst, Dr. Pawel Stanczak, Prof. Dr. Raymond C. Stevens and Prof. Dr. Kurt Wüthrich β2-Adrenergic Receptor Solutions for Structural Biology Analyzed with Microscale NMR Diffusion Measurements Angewandte Chemie International Edition 52

Article first published online: 24 OCT 2012 | DOI: 10.1002/anie.201205474

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Microcoil NMR measurements were performed to determine the final composition of solutions of the β2-adrenergic receptor (β2AR) reconstituted with a detergent and to study the hydrodynamic properties of the detergent micelles containing β2AR (see picture). Standards are established for the reproducible preparation of G-protein-coupled receptor solutions for crystallization trials and solution NMR studies.

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