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Dr. Qi An, Jenny Brinkmann, Prof.Dr. Jurriaan Huskens, Sven Krabbenborg, Prof. Dr. Jan de Boer and Dr. Pascal Jonkheijm A Supramolecular System for the Electrochemically Controlled Release of Cells Angewandte Chemie International Edition 51

Version of Record online: 4 NOV 2012 | DOI: 10.1002/anie.201205651

Thumbnail image of graphical abstract

Please release me: Electrochemically activated cell release is achieved using a redox-active supramolecular complex (see picture). Host molecule CB[8] (green) links surface-bound viologen (purple) with solution-exposed RGD peptides (red). Electrochemical reduction dissociates the complex, releases the peptides, and thus releases the cells from the substrates. This supramolecular strategy is also applicable to microelectrodes.

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