E-mail a Wiley Online Library Link

Prof. Dr. G. K. Surya Prakash, Dr. Somesh K. Ganesh, John-Paul Jones, Dr. Aditya Kulkarni, Kamil Masood, Joseph K. Swabeck and Prof. Dr. George A. Olah Copper-Mediated Difluoromethylation of (Hetero)aryl Iodides and β-Styryl Halides with Tributyl(difluoromethyl)stannane Angewandte Chemie International Edition 51

Version of Record online: 25 OCT 2012 | DOI: 10.1002/anie.201205850

Thumbnail image of graphical abstract

Owing to their unique properties, molecules containing the difluoromethyl group (CF2H) are of great interest. Tributyl(difluoromethyl)stannane has now been used for the selective and efficient direct ipso difluoromethylation of aryl iodides, heterocyclic iodides, and β-styryl halides (see scheme). The straightforward preparation of the difluoromethylating reagent makes this approach particularly valuable.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field