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Dr. Jun Qian, Dan Wang, Fu-Hong Cai, Dr. Wang Xi, Li Peng, Zhen-Feng Zhu, Dr. Hao He, Prof. Ming-Lie Hu and Prof. Sailing He Observation of Multiphoton-Induced Fluorescence from Graphene Oxide Nanoparticles and Applications in In Vivo Functional Bioimaging Angewandte Chemie International Edition 51

Article first published online: 24 SEP 2012 | DOI: 10.1002/anie.201206107

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Lightening organelles: A femtosecond laser can excite multiphoton-induced luminescence of graphene oxide nanoparticles. The flow, distributions, and clearance of intravenously injected GO-PEG nanoparticles in the blood vessel of mice could be observed clearly by two-photon imaging. The 3D distribution of microinjected GO-PEG nanoparticles in a mice brain could also be reconstructed with two-photon microscopy.

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