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Fei Peng, Dr. Yuanyuan Su, Xinpan Wei, Yimei Lu, Yanfeng Zhou, Yiling Zhong, Prof. Shuit-Tong Lee and Prof. Yao He Silicon-Nanowire-Based Nanocarriers with Ultrahigh Drug-Loading Capacity for In Vitro and In Vivo Cancer Therapy Angewandte Chemie International Edition 52

Version of Record online: 11 DEC 2012 | DOI: 10.1002/anie.201206737

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A pratical agent for cancer therapy: Silicon nanowires (SiNWs) were employed in the design of high-performance drug nanocarriers. The SiNWs were used as nanovectors for the delivery of an anticancer drug (DOX). SiNWs feature an ultrahigh drug-loading capacity. In vitro and in vivo experiments show that SiNW-based nanocarriers are highly efficacious for cancer therapy (see picture).

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