Dr. Alberto Rodríguez-Pulido, Alina I. Kondrachuk, Dr. Deepak K. Prusty, Jia Gao, Prof. Dr. Maria A. Loi and Prof. Dr. Andreas Herrmann Light-Triggered Sequence-Specific Cargo Release from DNA Block Copolymer–Lipid Vesicles Angewandte Chemie International Edition 52
Vesicle buster: Versatile functionalized nanocontainers, based on the stable incorporation of 22 mer DNA-b-PPO block copolymers (DBCs) into lipid vesicles, are presented (see picture). The study shows effective and sequence-specific cargo release from the DBC–lipid vesicles. Hybridization of these vesicles with an oligonucleotide photosensitizer allows for singlet oxygen generation upon irradiation, which induces cargo release.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf