E-mail

E-mail a Wiley Online Library Link

Jaganathan Karthikeyan, Radhakrishnan Haridharan and Prof. Dr. Chien-Hong Cheng Rhodium(III)-Catalyzed Oxidative C[BOND]H Coupling of N-Methoxybenzamides with Aryl Boronic Acids: One-Pot Synthesis of Phenanthridinones Angewandte Chemie International Edition 51

Article first published online: 26 OCT 2012 | DOI: 10.1002/anie.201206890

Thumbnail image of graphical abstract

General solution: An efficient rhodium-catalyzed dual C[BOND]H bond activation and cyclization of N-methoxybenzamides 1 with aryl boronic acids 2 (see scheme; Cp*=Me5C5) provides a straightforward and general approach to the phenanthridinone structure, which occurs widely in natural products and drugs. Highly regioselective C[BOND]C and C[BOND]N bond formation under mild conditions afforded a wide range of substituted phenanthridinones 3.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH