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Tracy W. Liu, Thomas D. MacDonald, Dr. Jiyun Shi, Prof.Dr. Brian C. Wilson and Prof.Dr. Gang Zheng Intrinsically Copper-64-Labeled Organic Nanoparticles as Radiotracers Angewandte Chemie International Edition 51

Article first published online: 14 NOV 2012 | DOI: 10.1002/anie.201206939

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PET friendly: Labels for PET imaging are incorporated into completely organic porphysomes by using a fast (30 min), one-pot, high-yielding (>95 %) procedure to produce highly stable (>48 h) radiolabeled nanoparticles that show the highest specific activity ever reported for a 64Cu-labeled nanoparticle. These 64Cu-porphysomes can be accurately and noninvasively tracked in vivo.

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