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Xiangling Xiong, Dr. Haipeng Liu, Dr. Zilong Zhao, Dr. Meghan B. Altman, Dr. Dalia Lopez-Colon, Prof. Chaoyong James Yang, Prof. Lung-Ji Chang, Prof. Chen Liu and Prof. Weihong Tan DNA Aptamer-Mediated Cell Targeting Angewandte Chemie International Edition 52

Version of Record online: 11 DEC 2012 | DOI: 10.1002/anie.201207063

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An apt modification: A simple and effective way to modify the cell surface with target-specific ligands, such as DNA aptamers, while minimizing the effects on the modified cells has been developed. After incubating with lipo–aptamer probes, immune cells (red, see scheme) recognize and kill cancer cells (blue) in the cell mixture.

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