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Dr. Yousuke Takaoka, Prof. Dr. Akio Ojida and Prof. Dr. Itaru Hamachi Protein Organic Chemistry and Applications for Labeling and Engineering in Live-Cell Systems Angewandte Chemie International Edition 52

Version of Record online: 20 FEB 2013 | DOI: 10.1002/anie.201207089

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Labels of the reconstruction: Chemical modification of proteins with synthetic probes is a powerful means of elucidating protein functions in live cells and of influencing these functions. New reactions that can be successfully applied in living systems represent a worthy challenge to organic chemistry, especially as the labeling and manipulation of endogenous proteins in their natural habitats is currently at an early stage.

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