Dipl.-Chem. Mario Stein and Prof. Dr. Bernhard Breit Catalytic Hydrogenation of Amides to Amines under Mild Conditions Angewandte Chemie International Edition 52
Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd–Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines.
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