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Yuan Zhang, Dr. Jun Qian, Dan Wang, Yalun Wang and Prof. Sailing He Multifunctional Gold Nanorods with Ultrahigh Stability and Tunability for In Vivo Fluorescence Imaging, SERS Detection, and Photodynamic Therapy Angewandte Chemie International Edition 52

Version of Record online: 11 DEC 2012 | DOI: 10.1002/anie.201207909

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Multimodal: Gold nanorods are coated with silica/polymer mutilayers, doped with surface-enhance Raman scattering (SERS) and fluorescence agents as well as photosensitizers. The structural and optical properties are tunable and stable in solutions and in living bodies. A real-time and specific in vivo SERS and fluorescence detection method using this structure is applied for tumor detection and subsequent photodynamic therapy (PDT).

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