E-mail a Wiley Online Library Link

Sanjun Shi, Lu Han, Prof. Tao Gong, Prof. Zhirong Zhang and Prof. Xun Sun Systemic Delivery of microRNA-34a for Cancer Stem Cell Therapy Angewandte Chemie International Edition 52

Version of Record online: 28 FEB 2013 | DOI: 10.1002/anie.201208077

Thumbnail image of graphical abstract

Delivered: A solid lipid nanoparticle (SLN) system was developed to deliver microRNA-34a (miR-34a) relevant for cancer stem cell (CSC) therapy into lung tissues. In miR-34a-containing SLNs (miSLNs-34a), miR-34a is protected from degradation in the serum and its cellular-transfection efficiency in vitro is increased. Thus, treatment with miSLNs-34a results in a higher probability of survival of CSC-bearing mice (see picture).

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field