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Dr. Jeroen Gillard, Johannes Frenkel, Valerie Devos, Prof. Dr. Koen Sabbe, Carsten Paul, Dr. Martin Rempt, Prof. Dr. Dirk Inzé, Prof. Dr. Georg Pohnert, Prof. Dr. Marnik Vuylsteke and Prof. Dr. Wim Vyverman Metabolomics Enables the Structure Elucidation of a Diatom Sex Pheromone Angewandte Chemie International Edition 52

Version of Record online: 12 DEC 2012 | DOI: 10.1002/anie.201208175

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Finding a mate: Diatoms use chemical signals to sense the presence of and find their mating partners. When the metabolic profiles of sexually active and inactive cells were compared, a highly up-regulated metabolite generated in the attracting mating type was identified as di-L-prolyl diketopiperazine, the first diatom pheromone.

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