E-mail a Wiley Online Library Link

Dr. Dung T. Dang, Dr. Hoang D. Nguyen, Dr. Maarten Merkx and Prof. Dr. Luc Brunsveld Supramolecular Control of Enzyme Activity through Cucurbit[8]uril-Mediated Dimerization Angewandte Chemie International Edition 52

Version of Record online: 25 JAN 2013 | DOI: 10.1002/anie.201208239

Thumbnail image of graphical abstract

At the double: Cucurbit[8]uril-mediated protein dimerization enables reversible control over strong enzyme activation of caspases. Simple addition of a short N-terminal FGG motif allows for a supramolecular-mediated 50-fold enhancement of caspase-9 catalytic activity.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field