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Dr. Jie He, Zengjiang Wei, Lei Wang, Zuleykhan Tomova, Taarika Babu, Prof. Dr. Chaoyang Wang, Prof. Dr. Xiaojun Han, Prof. Dr. John T. Fourkas and Prof. Dr. Zhihong Nie Hydrodynamically Driven Self-Assembly of Giant Vesicles of Metal Nanoparticles for Remote-Controlled Release Angewandte Chemie International Edition 52

Article first published online: 30 JAN 2013 | DOI: 10.1002/anie.201208425

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The hydrodynamics of laminar flow in a microfluidic device has been used to control the continuous self-assembly of gold nanoparticles (NPs) tethered with amphiphilic block copolymers. Spherical micelles, giant vesicles (500 nm–2.0 μm), or disk-like micelles could be formed by varying the flow rates of fluids. Such vesicles can release encapsulated hydrophilic species by using near-IR light (see picture).

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