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Dr. Nitin T. Patil, Valmik S. Shinde and Dr. Balasubramanian Sridhar Relay Catalytic Branching Cascade: A Technique to Access Diverse Molecular Scaffolds Angewandte Chemie International Edition 52

Article first published online: 17 JAN 2013 | DOI: 10.1002/anie.201208738

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Skeletal diversity: The reactions of alkynoic acids (A, common type of substrates) with various scaffold-building agents (B) under gold catalysis produce a series of multifunctional polyheterocyclic structures (see scheme). The approach enables the preparation of compound libraries with high skeletal diversity.

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