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Prof. Dr. Lutz F. Tietze, Tim Hungerland, Christoph Eichhorst, Dr. Alexander Düfert, Christian Maaß and Prof. Dr. Dietmar Stalke Efficient Synthesis of Helical Tetrasubstituted Alkenes as Potential Molecular Switches: A Two-Component Palladium-Catalyzed Triple Domino Process Angewandte Chemie International Edition 52

Version of Record online: 18 FEB 2013 | DOI: 10.1002/anie.201209510

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Fast and easy: Various helical tetrasubstituted alkenes were synthesized by a palladium-catalyzed domino process. The domino process consists of a Sonogashira reaction, a carbopalladation, and a direct C[BOND]H functionalization.

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