E-mail

E-mail a Wiley Online Library Link

Dr. Serena Mazzucchelli, Dr. Miriam Colombo, Paolo Verderio, Ewa Rozek, Francesco Andreata, Elisabetta Galbiati, Prof. Paolo Tortora, Prof. Fabio Corsi and Dr. Davide Prosperi Orientation-Controlled Conjugation of Haloalkane Dehalogenase Fused Homing Peptides to Multifunctional Nanoparticles for the Specific Recognition of Cancer Cells Angewandte Chemie International Edition 52

Version of Record online: 5 FEB 2013 | DOI: 10.1002/anie.201209662

Thumbnail image of graphical abstract

In control: The ligand positioning and orientation on multifunctional nanoparticles (MNP) are controlled by using a versatile bimodular approach that exploits an 11 amino acid (U11) homing peptide genetically fused with a haloalkane dehalogenase (HALO) enzyme. The resultant nanoparticles have good targeting efficiency and selectivity toward broadly occurring urokinase plasminogen activator receptor positive human cancer cells.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH