E-mail a Wiley Online Library Link

Dipl.-Biol. Sebastian W. Fuchs, Dipl.-Bioinf. Kenan A. J. Bozhüyük, Dipl.-Bioinf. Darko Kresovic, Florian Grundmann, M. Sc. Veronica Dill, Dr. Alexander O. Brachmann, Dr. Nicholas R. Waterfield and Prof. Dr. Helge B. Bode Formation of 1,3-Cyclohexanediones and Resorcinols Catalyzed by a Widely Occuring Ketosynthase Angewandte Chemie International Edition 52

Version of Record online: 19 FEB 2013 | DOI: 10.1002/anie.201210116

Thumbnail image of graphical abstract

Overlooked, but widespread! A new class of ketosynthases (DarB) involved in the biosynthesis of 1,3-cyclohexanediones and dialkylresorcinols has been identified and characterized in detail. The presence of homologues in 89 different bacteria, including several pathogens, reveals that DarB as well as the corresponding natural products might be widespread, thus presenting a new but so far overlooked pathway to natural products.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field