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Joost Snijder, Dr. Rebecca J. Rose, Dr. David Veesler, Prof. Dr. John E. Johnson and Prof. Dr. Albert J. R. Heck Studying 18 MDa Virus Assemblies with Native Mass Spectrometry Angewandte Chemie International Edition 52

Article first published online: 28 FEB 2013 | DOI: 10.1002/anie.201210197

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Setting records: Native mass spectometry was used to study the assembly of the 18 MDa capsid of bacteriophage HK97. The previous record for the analysis of capsids by this method was around 10 MDa. The results indicate that the efficiency of desolvation is the main priority in improving native MS instrumentation.

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