E-mail a Wiley Online Library Link

Caroline Aldag, Markus J. Bröcker, Michael J. Hohn, Laure Prat, Gifty Hammond, Abigail Plummer and Dieter Söll Back Cover: Rewiring Translation for Elongation Factor Tu-Dependent Selenocysteine Incorporation (Angew. Chem. Int. Ed. 5/2013) Angewandte Chemie International Edition 52

Version of Record online: 20 JAN 2013 | DOI: 10.1002/anie.201300063

Thumbnail image of graphical abstract

Synthetic tRNA for selenoprotein production is described by D. Söll et al. in their Communication on page 1441 ff. The tRNA is a substrate for three E. coli proteins: seryl-tRNA synthetase (SerRS), selenocysteine synthase (SelA) generating Sec-tRNAUTu, and EF-Tu for Sec-tRNAUTu transport to the ribosome, which allows site-specific Sec insertion into proteins. This system has general utility in protein engineering, molecular biology, and disease research.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field