E-mail

E-mail a Wiley Online Library Link

Dr. Mao Chen and Prof. Dr. Stephen L. Buchwald Continuous-Flow Synthesis of 1-Substituted Benzotriazoles from Chloronitrobenzenes and Amines in a C[BOND]N Bond Formation/Hydrogenation/Diazotization/Cyclization Sequence Angewandte Chemie International Edition 52

Version of Record online: 1 MAR 2013 | DOI: 10.1002/anie.201300615

Thumbnail image of graphical abstract

Two approaches have been developed for the regiospecific continuous-flow synthesis of 1-substituted benzotriazoles. They begin with either an SNAr reaction at high temperature or Pd catalysis and involve consecutive multiphase processes, allowing the multistep synthesis of benzotriazoles to take place in an efficient manner (see picture).

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH