Dr. Zhe Liu, Prof.Dr. Robert J. Deeth, Jennifer S. Butler, Dr. Abraha Habtemariam, Prof. Dr. Mark E. Newton and Prof. Dr. Peter J. Sadler Reduction of Quinones by NADH Catalyzed by Organoiridium Complexes Angewandte Chemie International Edition 52
One electron at a time: Half-sandwich organometallic cyclopentadienyl–IrIII complexes containing N,N-chelated ligands can catalyze the reduction of quinones (Q), such as vitamin K3, to semiquinones (Q.−) by coenzyme NADH (see picture). DFT calculations suggest that the mechanism involves hydride transfer followed by two one-electron transfers and the unusual IrII oxidation state as a key transient intermediate.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf