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Dr. Xiaoming Jie, Yaping Shang, Peng Hu and Prof. Dr. Weiping Su Cover Picture: Palladium-Catalyzed Oxidative Cross-Coupling between Heterocycles and Terminal Alkynes with Low Catalyst Loading (Angew. Chem. Int. Ed. 13/2013) Angewandte Chemie International Edition 52

Version of Record online: 21 FEB 2013 | DOI: 10.1002/anie.201301067

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The direct alkynylation of electron-rich aromatic heterocycles with terminal alkynes was accomplished in high yields and good selectivity when using a low loading of palladium catalyst, as described by W. Su and co-workers in their Communication on page 3630 ff. A high loading of palladium catalyst led to poor yields because of the undesired homocoupling of alkynes.

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