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Dr. Dongbing Zhao, Dr. Zhuangzhi Shi and Prof. Dr. Frank Glorius Indole Synthesis by Rhodium(III)-Catalyzed Hydrazine-Directed C[BOND]H Activation: Redox-Neutral and Traceless by N[BOND]N Bond Cleavage Angewandte Chemie International Edition 52

Article first published online: 25 SEP 2013 | DOI: 10.1002/anie.201306098

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Fishing for complements! There is an alternative to the useful Fischer indole synthesis. The new method utilizes the same retrosynthetic disconnection but is based on a RhIII-catalyzed directed C[BOND]H activation step and a successive coupling with alkynes.

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