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Wei Cui, Dr. Yue Cui, Dr. Pengli Zhu, Dr. Jie Zhao, Dr. Ying Su, Dr. Yang Yang and Prof. Dr. Junbai Li An Anticoagulant Activity System Using Nanoengineered Autofluorescent Heparin Nanotubes Chemistry – An Asian Journal 7

Article first published online: 26 OCT 2011 | DOI: 10.1002/asia.201100425

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The bleeding edge: Periodate-oxidized heparin (O-HEP) and chitosan (CHI) were assembled alternatively into the pore of polycarbonate membranes to form nanotube structures through a layer-by-layer method (see graphic). O-HEP/CHI nanotubes display an autofluorescent property without the addition of any fluorescent dye. They also have a lower anticoagulant activity.

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