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Dylan M. Owen, Astrid Magenau, David Williamson and Katharina Gaus The lipid raft hypothesis revisited – New insights on raft composition and function from super-resolution fluorescence microscopy BioEssays 34

Article first published online: 14 JUN 2012 | DOI: 10.1002/bies.201200044

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We review how new super-resolution fluorescence microscopy methods such as photoactivated localisation microscopy (PALM), stimulated emission depletion (STED) microscopy and structured illumination microscopy (SIM) are being used to study membrane organisation. We especially focus on ordered-phase lipid microdomains (lipid rafts) and their role in regulating protein distribution and diffusion.

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