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Sean Vincent Murphy and Anthony Atala Organ engineering – combining stem cells, biomaterials, and bioreactors to produce bioengineered organs for transplantation BioEssays 35

Article first published online: 20 SEP 2012 | DOI: 10.1002/bies.201200062

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The goal of organ engineering is to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. Recent progress in stem cell biology, biomaterials and processes such as organ decellularization and electrospinning has resulted in the generation of bioengineered replacement tissues and organs for patients.

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