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Cathy A. Wyse Does human evolution in different latitudes influence susceptibility to obesity via the circadian pacemaker? BioEssays 34

Article first published online: 30 AUG 2012 | DOI: 10.1002/bies.201200067

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The variable photoperiods of Northern latitudes challenge the entrainment capacity of the circadian pacemaker, which evolved under constant photoperiods in Equatorial regions. Entrainment to the erratic photoperiods facilitated by artificial light presents an additional challenge. Metabolic dysfunction and obesity are potential consequences of such desynchronization of circadian and environmental rhythms.

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