Alicia A. Bicknell, Can Cenik, Hon N. Chua, Frederick P. Roth and Melissa J. Moore Introns in UTRs: Why we should stop ignoring them BioEssays 34
Whereas introns in coding regions are well-appreciated for their role in producing alternative protein isoforms, introns in untranslated regions (UTRs) have been largely ignored. Recent evidence shows that UTR introns are important for regulating gene expression; introns in 5′-UTRs control mRNA nuclear export, and introns in 3′-UTRs regulate mRNA stability.
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