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Alicia A. Bicknell, Can Cenik, Hon N. Chua, Frederick P. Roth and Melissa J. Moore Introns in UTRs: Why we should stop ignoring them BioEssays 34

Version of Record online: 26 OCT 2012 | DOI: 10.1002/bies.201200073

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Whereas introns in coding regions are well-appreciated for their role in producing alternative protein isoforms, introns in untranslated regions (UTRs) have been largely ignored. Recent evidence shows that UTR introns are important for regulating gene expression; introns in 5′-UTRs control mRNA nuclear export, and introns in 3′-UTRs regulate mRNA stability.

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