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Vadim N. Gladyshev On the cause of aging and control of lifespan BioEssays 34

Version of Record online: 23 AUG 2012 | DOI: 10.1002/bies.201200092

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What the causes of aging are and which factors define species lifespan are key questions in the understanding of aging. The author describes a concept that heterogeneity leads to inevitable damage accumulation causing aging, and that control of damage composition and rate of accumulation define lifespan.

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