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Helen K. Matthews and Buzz Baum The metastatic cancer cell cortex: An adaptation to enhance robust cell division in novel environments? BioEssays 34

Version of Record online: 20 SEP 2012 | DOI: 10.1002/bies.201200109

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To metastasize, cancer cells must be able to complete cell division in environments very different from their tissue of origin. We suggest that mitotic cell rounding, aided by several actin-regulatory oncogenes, may facilitate this process in a robust, context-independent manner.

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