E-mail

E-mail a Wiley Online Library Link

Rahul K. Das, Anuradha Mittal and Rohit V. Pappu How is functional specificity achieved through disordered regions of proteins? BioEssays 35

Article first published online: 9 NOV 2012 | DOI: 10.1002/bies.201200115

Thumbnail image of graphical abstract

N-terminal disordered regions control inactivation of potassium channels. The mechanism of inactivation is different for BK channel versus Shaker channels. The former populates an O* state that shows intermediate activity. Adaptation of existing phenomenological models for coupled folding and binding explains channel-specific differences in N-type inactivation through disordered regions.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH