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Marc Thilo Figge, Heinz D. Osiewacz and Andreas S. Reichert Quality control of mitochondria during aging: Is there a good and a bad side of mitochondrial dynamics? BioEssays 35

Version of Record online: 29 JAN 2013 | DOI: 10.1002/bies.201200125

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Mitochondria are essential eukaryotic organelles that represent a cellular “achilles heel”. Different pathways are active keeping mitochondria functional over time, including cycles of fusion and fission. We hypothesize that during aging mitochondrial dynamics may not only be beneficial but represents a double-edged sword with a good and a bad side.

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