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Patricia Resa-Infante and Gülsah Gabriel The nuclear import machinery is a determinant of influenza virus host adaptation BioEssays 35

Article first published online: 21 NOV 2012 | DOI: 10.1002/bies.201200138

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Importin-α isoforms possess multiple functions carried out on both sites of the nuclear envelope. Influenza viruses utilize importin-α functions directly related to the nuclear import of cargo proteins or other functions beyond transport to regulate polymerase activity in the nucleus of the host cell.

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