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Cheuk T. Leung Epithelial cell translocation: New insights into mechanisms of tumor initiation BioEssays 35

Article first published online: 19 DEC 2012 | DOI: 10.1002/bies.201200151

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A cell translocation mechanism displaces sporadic mutant cells from normal, suppressive epithelial environment during early steps of tumor initiation. This epithelial cell translocation process exerts a selective pressure on early mutant cells to survive and grow in new microenvironment outside of their native niches.

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